Lucas T. Jennelle, Ph.D.

Affiliations: 
2013 Biomedical Sciences The George Washington University, Washington, DC, United States 
Area:
Virology, Molecular Biology
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"Lucas Jennelle"

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Michael Bukrinsky grad student 2013 The George Washington University
 (Contribution of Calnexin to HIV-1 Nef effects on ABCA1.)
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Pushkarsky T, Shilov E, Kruglova N, et al. (2016) Accumulation of neutral lipids in liver and aorta of Nef-transgenic mice. Aids Research and Human Retroviruses
Jennelle L, Hunegnaw R, Dubrovsky L, et al. (2014) HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin. The Journal of Biological Chemistry. 289: 28870-84
Jennelle L, Hunegnaw R, Dubrovsky L, et al. (2014) 136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin Jaids Journal of Acquired Immune Deficiency Syndromes. 65: 57
Bukrinsky M, Jennelle L, Brichacek B, et al. (2014) HIV-1 protein Nef impairs cellular cholesterol efflux by disrupting the interaction between abca1 and calnexin Atherosclerosis. 235: e21
Jennelle L, Hunegnaw R, Sviridov D, et al. (2013) HIV-1 Nef targets calnexin: a novel mechanism behind Nef effects on host cell and viral proteins Retrovirology. 10
Cui HL, Grant A, Mukhamedova N, et al. (2012) HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux. Journal of Lipid Research. 53: 696-708
Jennelle L, Bukrinsky M. (2011) Critical role of calnexin in Nef-mediated inactivation of ABCA1 Retrovirology. 8
Morrow MP, Grant A, Mujawar Z, et al. (2010) Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1. Molecular Pharmacology. 78: 215-25
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