Erich E. Wanker

Affiliations: 
Max Delbruck Center for Molecular Medicine, Berlin, Berlin, Berlin, Germany 
Area:
Neurodegenerative diseases, proteomics
Website:
http://www.mdc-berlin.de/en/research/research_teams/proteomics_and_molecular_mechanisms_of_neurodegenerative_diseases/index.html
Google:
"Erich Wanker"
Bio:

since 2001 Full Professorship (C4) of Molecular Medicine at Charité Berlin and Head of
Neuroproteomics Group at the Max Delbrueck Center for Molecular Medicine
1999 - 2001 Independent Group Leader (C3) at the Max Planck Institute for Molecular
Genetics, Berlin
1995 – 1999 Group Leader at Max Planck Institute for Molecular Genetics
1993 - 1995 Postdoctoral fellow at the Dept. of Biochemistry, University of California, los
Angeles, USA
1990 - 1992 Research Assistant at the Dept. of Biotechnology, Technical University of
Graz, Austria
1989 – 1992 PhD thesis, Dept. of Biotechnology, Technical University of Graz, Austria

Mean distance: 26716.5 (cluster 31)
 
Cross-listing: Chemistry Tree

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Publications

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Bonsor M, Ammar O, Schnoegl S, et al. (2024) Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects. Proteomics. e2300114
Alteen MG, Deme JC, Alvarez CP, et al. (2023) Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Structure (London, England : 1993)
Secker C, Motzny AY, Kostova S, et al. (2023) The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation. Journal of Neurochemistry
Smith EJ, Sathasivam K, Landles C, et al. (2023) Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches. Brain Communications. 5: fcad010
Greco TM, Secker C, Ramos ES, et al. (2022) Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. Cell Systems
Klockmeier K, Silva Ramos E, Raskó T, et al. (2021) Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells. Journal of Molecular Biology. 167184
Schindler F, Praedel N, Neuendorf N, et al. (2021) Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington's Disease Knock-in Mice. Frontiers in Neuroscience. 15: 682172
Poh J, Ponsford AH, Boyd J, et al. (2020) A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation. Redox Biology. 37: 101686
Haenig C, Atias N, Taylor AK, et al. (2020) Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Reports. 32: 108050
Rieux M, Alpaugh M, Sciacca G, et al. (2020) Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology. Molecular Psychiatry
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