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Daya Perkins, Ph.D.

Affiliations: 
2010 Molecular Pharmacology and Toxicology University of Southern California, Los Angeles, CA, United States 
Area:
Neuroscience
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"Daya Perkins"
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Ronald L. Alkana grad student 2010 USC
 (The structure of Loop 2 is important for agonist and ethanol sensitivity in glycine and GABAA receptors.)

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Naito A, Muchhala KH, Asatryan L, et al. (2014) Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research. Molecular Pharmacology. 86: 635-46
Perkins DI, Trudell JR, Asatryan L, et al. (2012) Charge and geometry of residues in the loop 2 β hairpin differentially affect agonist and ethanol sensitivity in glycine receptors. The Journal of Pharmacology and Experimental Therapeutics. 341: 543-51
Asatryan L, Popova M, Perkins D, et al. (2010) Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors. The Journal of Pharmacology and Experimental Therapeutics. 334: 720-8
Perkins DI, Trudell JR, Crawford DK, et al. (2010) Molecular targets and mechanisms for ethanol action in glycine receptors. Pharmacology & Therapeutics. 127: 53-65
Perkins DI, Trudell JR, Crawford DK, et al. (2009) Loop 2 structure in glycine and GABA(A) receptors plays a key role in determining ethanol sensitivity. The Journal of Biological Chemistry. 284: 27304-14
Crawford DK, Perkins DI, Trudell JR, et al. (2008) Roles for loop 2 residues of alpha1 glycine receptors in agonist activation. The Journal of Biological Chemistry. 283: 27698-706
Perkins DI, Trudell JR, Crawford DK, et al. (2008) Targets for ethanol action and antagonism in loop 2 of the extracellular domain of glycine receptors. Journal of Neurochemistry. 106: 1337-49
Li K, Xu L, Kulkarni AA, et al. (2008) Ethanol inhibits functional activity of the human intestinal dipeptide transporter hPepT1 expressed in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 32: 777-84
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