Francis A. Concepcion, Ph.D.

Affiliations: 
2007 Cell and Neurobiology: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Neuroscience
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"Francis Concepcion"
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Jeannie Chen grad student 2007 USC
 (Essential role of the carboxyl -terminus for proper rhodopsin trafficking and "enlightenment" to the pathway(s) causing retinal degeneration in a mouse model expressing a truncated rhodopsin mutant.)
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Publications

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Chen J, Woodruff ML, Wang T, et al. (2010) Channel modulation and the mechanism of light adaptation in mouse rods. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16232-40
Concepcion F, Chen J. (2010) Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration. Plos One. 5: e10904
Mojumder DK, Concepcion FA, Patel SK, et al. (2010) Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Investigative Ophthalmology & Visual Science. 51: 5796-803
Chen J, Shi G, Concepcion FA, et al. (2006) Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa Journal of Neuroscience. 26: 11929-11937
Shi GW, Chen J, Concepcion F, et al. (2005) Light causes phosphorylation of nonactivated visual pigments in intact mouse rod photoreceptor cells. The Journal of Biological Chemistry. 280: 41184-91
Concepcion F, Mendez A, Chen J. (2002) The carboxyl-terminal domain is essential for rhodopsin transport in rod photoreceptors. Vision Research. 42: 417-26
Eversole-Cire P, Concepcion FA, Simon MI, et al. (2000) Synergistic effect of Bcl-2 and BAG-1 on the prevention of photoreceptor cell death. Investigative Ophthalmology & Visual Science. 41: 1953-61
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