Leonard W. Seymour
Affiliations: | University of Oxford, Oxford, United Kingdom |
Area:
targeted delivery of drugs and genes to tumorsWebsite:
http://www.gene-delivery.ox.ac.uk/Google:
"Leonard Seymour"Mean distance: 19430.2
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Publications
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| Dyer A, Schoeps B, Frost S, et al. (2018) Antagonism of glycolysis and reductive carboxylation of glutamine potentiates activity of oncolytic adenoviruses in cancer cells. Cancer Research |
| Freedman JD, Duffy MR, Lei-Rossmann J, et al. (2018) An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells. Cancer Research |
| Scott EM, Duffy MR, Freedman JD, et al. (2017) Solid Tumor Immunotherapy with T Cell Engager-Armed Oncolytic Viruses. Macromolecular Bioscience |
| O'Cathail SM, Pokrovska TD, Maughan TS, et al. (2017) Combining Oncolytic Adenovirus with Radiation-A Paradigm for the Future of Radiosensitization. Frontiers in Oncology. 7: 153 |
| Freedman JD, Hagel J, Scott EM, et al. (2017) Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies. Embo Molecular Medicine |
| Dyer A, Di Y, Calderon H, et al. (2017) Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Molecular Therapy Oncolytics. 4: 18-30 |
| Chia SL, Lei J, Ferguson DJ, et al. (2017) Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer. Virology. 505: 162-171 |
| Seymour LW, Fisher KD. (2016) Oncolytic viruses: finally delivering. British Journal of Cancer |
| Tedcastle A, Illingworth S, Brown A, et al. (2015) Actin resistant DNAse I expression from oncolytic adenovirus Enadenotucirev enhances its intratumoural spread and reduces tumour growth. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Lynn GM, Laga R, Darrah PA, et al. (2015) In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nature Biotechnology. 33: 1201-10 |