Sarah Hughes

Affiliations: 
University of Alberta, Edmonton, Alberta, Canada 
Area:
Tumor suppressors
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"Sarah Hughes"

Parents

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Rick Fehon post-doc 2001-2005 Duke
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Publications

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Keegan SE, Hughes SC. (2020) Role of nuclear-cytoplasmic protein localization during Drosophila neuroblast development. Genome
Abeysundara N, Simmonds AJ, Hughes SC. (2017) Moesin is involved in polarity maintenance and cortical remodelling during asymmetric cell division. Molecular Biology of the Cell
Hughes SK, Oudin MJ, Tadros J, et al. (2015) PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena. Molecular Biology of the Cell
Abeysundara N, Leung AC, Primrose DA, et al. (2014) Regulation of cell proliferation and adhesion by means of a novel region of drosophila merlin interacting with Sip1. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 1554-70
Yang Y, Primrose DA, Leung AC, et al. (2012) The PP1 phosphatase flapwing regulates the activity of Merlin and Moesin in Drosophila. Developmental Biology. 361: 412-26
Hughes SC, Formstecher E, Fehon RG. (2010) Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity. Journal of Cell Science. 123: 1099-107
Hughes SC, Fehon RG. (2007) Understanding ERM proteins--the awesome power of genetics finally brought to bear. Current Opinion in Cell Biology. 19: 51-6
Hughes SC, Fehon RG. (2006) Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase. The Journal of Cell Biology. 175: 305-13
Speck O, Hughes SC, Noren NK, et al. (2003) Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature. 421: 83-7
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