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Troy L. Brady, Ph.D.

Affiliations: 
2007 Genetics, Development and Cell Biology Iowa State University, Ames, IA, United States 
Area:
Molecular Biology, Genetics
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Daniel F. Voytas grad student 2007 Iowa State
 (The role of the integrase C-terminus in replication and targeted integration of the yeast retrotransposon Ty5.)

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Publications

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Gupta K, Brady T, Dyer BM, et al. (2014) Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains. The Journal of Biological Chemistry. 289: 20477-88
Li X, Burnight ER, Cooney AL, et al. (2013) piggyBac transposase tools for genome engineering. Proceedings of the National Academy of Sciences of the United States of America. 110: E2279-87
Zhong L, Malani N, Li M, et al. (2013) Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction. Human Gene Therapy. 24: 520-5
Brady T, Kelly BJ, Male F, et al. (2013) Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays. Journal of Virological Methods. 189: 53-7
Pace MJ, Graf EH, Agosto LM, et al. (2012) Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency. Plos Pathogens. 8: e1002818
Scholler J, Brady TL, Binder-Scholl G, et al. (2012) Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Science Translational Medicine. 4: 132ra53
Bushman FD, Brady T, Malani N, et al. (2012) 134 HIV DNA Integration Jaids Journal of Acquired Immune Deficiency Syndromes. 59: 55
Schaller T, Ocwieja KE, Rasaiyaah J, et al. (2011) HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency Plos Pathogens. 7
Brady T, Bushman FD. (2011) Nondividing cells: a safer bet for integrating vectors? Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 640-1
Ocwieja KE, Brady TL, Ronen K, et al. (2011) HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2. Plos Pathogens. 7: e1001313
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