Andrew J. Castiglioni

Northwestern University, Evanston, IL 
Somatosensory system
"Andrew Castiglioni"
Mean distance: 14.71 (cluster 11)


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Diane Lipscombe grad student 1999-2006 Brown
 (Alternative splicing influences N -type calcium channel activity in the pain pathway.)
Jaime García-Añoveros post-doc 2006- Northwestern
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Spix B, Castiglioni AJ, Remis NN, et al. (2022) Whole-body analysis of TRPML3 (MCOLN3) expression using a GFP-reporter mouse model reveals widespread expression in secretory cells and endocrine glands. Plos One. 17: e0278848
Remis NN, Wiwatpanit T, Castiglioni AJ, et al. (2014) Mucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaning. Plos Genetics. 10: e1004833
Marangoudakis S, Andrade A, Helton TD, et al. (2012) Differential ubiquitination and proteasome regulation of Ca(V)2.2 N-type channel splice isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10365-9
Castiglioni AJ, Remis NN, Flores EN, et al. (2011) Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons. The Journal of Comparative Neurology. 519: 1095-114
Nagata K, Zheng L, Madathany T, et al. (2008) The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration. Proceedings of the National Academy of Sciences of the United States of America. 105: 353-8
Castiglioni AJ, García-Añoveros J. (2007) MechanoTRPs and TRPA1. Current Topics in Membranes. 59: 171-89
Altier C, Dale CS, Kisilevsky AE, et al. (2007) Differential role of N-type calcium channel splice isoforms in pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6363-73
Raingo J, Castiglioni AJ, Lipscombe D. (2007) Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors. Nature Neuroscience. 10: 285-92
Castiglioni AJ, Raingo J, Lipscombe D. (2006) Alternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channels. The Journal of Physiology. 576: 119-34
Bell TJ, Thaler C, Castiglioni AJ, et al. (2004) Cell-specific alternative splicing increases calcium channel current density in the pain pathway. Neuron. 41: 127-38
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