James Herrington

Affiliations: 
Merck Research Labs, Boston, MA, United States 
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"James Herrington"
Mean distance: 14.08 (cluster 11)
 
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Shao PP, Ye F, Chakravarty PK, et al. (2013) Improved Cav2.2 Channel Inhibitors through a gem-Dimethylsulfone Bioisostere Replacement of a Labile Sulfonamide. Acs Medicinal Chemistry Letters. 4: 1064-8
Shao PP, Ye F, Chakravarty PK, et al. (2012) Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain. Journal of Medicinal Chemistry. 55: 9847-55
Swensen AM, Herrington J, Bugianesi RM, et al. (2012) Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels. Molecular Pharmacology. 81: 488-97
Tyagarajan S, Chakravarty PK, Park M, et al. (2011) A potent and selective indole N-type calcium channel (Ca(v)2.2) blocker for the treatment of pain. Bioorganic & Medicinal Chemistry Letters. 21: 869-73
Abbadie C, McManus OB, Sun SY, et al. (2010) Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker. The Journal of Pharmacology and Experimental Therapeutics. 334: 545-55
Herrington J, Sanchez M, Wunderler D, et al. (2005) Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic beta-cells. The Journal of Physiology. 567: 159-75
Murphy JG, Herrington JN, Granger JP, et al. (2003) Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure. American Journal of Physiology. Heart and Circulatory Physiology. 284: H393-403
Babcock DF, Herrington J, Goodwin PC, et al. (1997) Mitochondrial participation in the intracellular Ca2+ network. The Journal of Cell Biology. 136: 833-44
Park YB, Herrington J, Babcock DF, et al. (1996) Ca2+ clearance mechanisms in isolated rat adrenal chromaffin cells. The Journal of Physiology. 492: 329-46
Herrington J, Park YB, Babcock DF, et al. (1996) Dominant role of mitochondria in clearance of large Ca2+ loads from rat adrenal chromaffin cells. Neuron. 16: 219-28
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