Christina Downey, Ph.D.
Affiliations: | 2010 | Cancer Biology | Wayne State University, Detroit, MI, United States |
Area:
Molecular Biology, Oncology, PathologyGoogle:
"Christina Downey"Parents
Sign in to add mentor| Marc D. Basson | grad student | 2010 | Wayne State | |
| (Molecular mechanisms of pressure-stimulated cancer cell signaling.) | ||||
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Publications
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| Basson MD, Zeng B, Downey C, et al. (2015) Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β. Molecular Oncology. 9: 513-26 |
| Basson MD, Zeng B, Downey C, et al. (2015) Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β Molecular Oncology. 9: 513-526 |
| Basson MD, Sirivelu M, Downey C, et al. (2014) Mo1654 Extracellular Pressure-Induced Increases in [Ca2+]i via T-Type CAV3.3 Channels Stimulate Cancer Cell Proliferation by Enhancing Activity of a PKCBeta-Dependent IKK, IKB, NF-kB Pathway Gastroenterology. 146: S-628 |
| Downey C, Craig DH, Basson MD. (2011) Isoform-specific modulation of pressure-stimulated cancer cell proliferation and adhesion by α-actinin American Journal of Surgery. 202: 520-523 |
| Downey C, Craig D, Basson M. (2011) In Vivo Forces Activate Circulating Cancer Cell Signaling To Promote Metastasis Journal of Surgical Research. 165: 336 |
| Downey C, Hatfield JS, Tepe J, et al. (2010) 40 Increased Extracellular Pressure Stimulates NF-kB Activation and Cellular Proliferation in Cancer Cells Gastroenterology. 138: S-8 |
| Craig DH, Owen CR, Conway WC, et al. (2008) Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice. The Journal of Clinical Investigation. 118: 3170-80 |
| Downey C, Craig DH, Basson MD. (2008) Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1. Cellular and Molecular Life Sciences : Cmls. 65: 1446-57 |
| Craig DH, Downey C, Basson MD. (2008) SiRNA-mediated reduction of alpha-actinin-1 inhibits pressure-induced murine tumor cell wound implantation and enhances tumor-free survival. Neoplasia (New York, N.Y.). 10: 217-22 |
| Craig DH, Downey C, Basson MD. (2008) S2051 SIRNA-Mediated Reduction of α-Actinin-1 Inhibits Pressure-Induced Murine Tumor Cell Wound Implantation and Enhances Tumor-Free Survival Gastroenterology. 134: A-305 |