James L. Howard

Affiliations: 
Burroughs Wellcome Co., NC, United States 
Area:
neuropsychopharmacology
Google:
"James Howard"
Mean distance: 16.16 (cluster 19)
 
SNBCP
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Owens SM, Pollard GT, Howard JL, et al. (2016) Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats. Acs Chemical Neuroscience
Runyon SP, Brieaddy LE, Mascarella SW, et al. (2010) Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activity. Journal of Medicinal Chemistry. 53: 5290-301
Beardsley PM, Pollard GT, Howard JL, et al. (2010) Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats. Psychopharmacology. 210: 189-98
Navarro HA, Howard JL, Pollard GT, et al. (2009) Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporter. British Journal of Pharmacology. 156: 1178-84
Carroll FI, Fox BS, Kuhar MJ, et al. (2006) Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self-administration after oral administration. European Journal of Pharmacology. 553: 149-56
Carroll FI, Runyon SP, Abraham P, et al. (2004) Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers. Journal of Medicinal Chemistry. 47: 6401-9
Carroll I, Thomas JB, Dykstra LA, et al. (2004) Pharmacological properties of JDTic: a novel kappa-opioid receptor antagonist. European Journal of Pharmacology. 501: 111-9
Carroll FI, Pawlush N, Kuhar MJ, et al. (2004) Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes. Journal of Medicinal Chemistry. 47: 296-302
Meade EA, Sznaidman M, Pollard GT, et al. (1998) Anxiolytic activity of analogues of 4-benzylamino-2-methyl-7H- pyrrolo[2,3-d]pyrimidines European Journal of Medicinal Chemistry. 33: 363-374
Rigdon GC, Norman MH, Cooper BR, et al. (1996) 1192U90 in animal tests that predict antipsychotic efficacy, anxiolysis, and extrapyramidal side effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 231-42
See more...