Jack D. Newman, Ph.D.

Affiliations: 
2001 University of Wisconsin, Madison, Madison, WI 
Area:
Microbiology Biology
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"Jack Newman"

Parents

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Timothy J. Donohue grad student 1994-2001 UW Madison
 (The sigma factor/anti-sigma factor pair, sigma(E)/ChrR in Rhodobacter sphaeroides.)
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Publications

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Kirby J, Dietzel KL, Wichmann G, et al. (2016) Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae. Metabolic Engineering
Horwitz AA, Walter JM, Schubert MG, et al. (2015) Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas. Cell Systems. 1: 88-96
Paddon CJ, Westfall PJ, Pitera DJ, et al. (2013) High-level semi-synthetic production of the potent antimalarial artemisinin. Nature. 496: 528-32
Westfall PJ, Pitera DJ, Lenihan JR, et al. (2012) Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. Proceedings of the National Academy of Sciences of the United States of America. 109: E111-8
Tsuruta H, Paddon CJ, Eng D, et al. (2009) High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. Plos One. 4: e4489
Anthony JR, Anthony LC, Nowroozi F, et al. (2009) Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. Metabolic Engineering. 11: 13-9
Ro DK, Ouellet M, Paradise EM, et al. (2008) Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. Bmc Biotechnology. 8: 83
Withers ST, Gottlieb SS, Lieu B, et al. (2007) Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. Applied and Environmental Microbiology. 73: 6277-83
Pitera DJ, Paddon CJ, Newman JD, et al. (2007) Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metabolic Engineering. 9: 193-207
Newman JD, Marshall J, Chang M, et al. (2006) High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli. Biotechnology and Bioengineering. 95: 684-91
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