Deborah N. Chadee

Affiliations: 
Biology (Cell-Molecular Biology) The University of Toledo 
Area:
Molecular Biology, Cell Biology, Oncology
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"Deborah Chadee"
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Publications

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Cedeno-Rosario L, Honda D, Sunderland AM, et al. (2022) Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division. The Journal of Biological Chemistry. 102263
Kasturirangan S, Mehdi B, Chadee DN. (2021) LATS1 Regulates MLK3 subcellular localization and MLK3-mediated invasion in ovarian epithelial cells. Molecular and Cellular Biology
Harmych SJ, Kumar J, Bouni ME, et al. (2020) Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells. Experimental Cell Research. 112167
Kankanamge D, Tennakoon M, Weerasinghe A, et al. (2019) G protein αq exerts expression level-dependent distinct signaling paradigms. Cellular Signalling. 58: 34-43
Schroyer AL, Stimes NW, Abi Saab WF, et al. (2017) MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells. Oncogene
Blessing NA, Kasturirangan S, Zink EM, et al. (2017) Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells. Cellular Signalling. 39: 66-73
Goh Q, Dearth CL, Corbett JT, et al. (2015) Intercellular adhesion molecule-1 expression by skeletal muscle cells augments myogenesis. Experimental Cell Research. 331: 292-308
Blessing NA, Brockman AL, Chadee DN. (2014) The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3. Molecular and Cellular Biology. 34: 3132-43
Chadee DN. (2013) Involvement of mixed lineage kinase 3 in cancer. Canadian Journal of Physiology and Pharmacology. 91: 268-74
Abi Saab WF, Brown MS, Chadee DN. (2012) MLK4β functions as a negative regulator of MAPK signaling and cell invasion. Oncogenesis. 1: e6
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