Valérie Morisset

"Valérie Morisset"
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Witty DR, Alvaro G, Derjean D, et al. (2020) Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia. Acs Medicinal Chemistry Letters. 11: 1678-1687
Zakrzewska JM, Palmer J, Bendtsen L, et al. (2018) Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience. Trials. 19: 704
Zakrzewska JM, Palmer J, Morisset V, et al. (2017) Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial. The Lancet. Neurology
Tanaka BS, Zhao P, Dib-Hajj FB, et al. (2016) A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia. Molecular Medicine (Cambridge, Mass.). 22
Zakrzewska JM, Palmer J, Ettlin DA, et al. (2013) Novel design for a phase IIa placebo-controlled, double-blind randomized withdrawal study to evaluate the safety and efficacy of CNV1014802 in patients with trigeminal neuralgia. Trials. 14: 402
Amaya F, Wang H, Costigan M, et al. (2006) The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12852-60
Lappin SC, Randall AD, Gunthorpe MJ, et al. (2006) TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation. European Journal of Pharmacology. 540: 73-81
Derjean D, Bertrand S, Le Masson G, et al. (2003) Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states. Nature Neuroscience. 6: 274-81
Morisset V, Urban L. (2001) Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. Journal of Neurophysiology. 86: 40-8
Morisset V, Nagy F. (2000) Plateau potential-dependent windup of the response to primary afferent stimuli in rat dorsal horn neurons. The European Journal of Neuroscience. 12: 3087-95
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