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David S. Ragsdale

Affiliations: 
Neurology and Neurosurgery McGill University, Montreal, QC, Canada 
Area:
Sodium Channels, Calcium Channels, Epilepsy
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"David Ragsdale"
Mean distance: 14.74 (cluster 6)
 		SNBCP
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Parents

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William A. Catterall grad student McGill

Children

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Newt Agrawal grad student Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada

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Publications

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Lévesque M, Ragsdale D, Avoli M. (2018) Evolving Mechanistic Concepts Of Epileptiform Synchronization And Their Relevance In Curing Focal Epileptic Disorders. Current Neuropharmacology
Mo G, Grant R, O'Donnell D, et al. (2011) Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C. Molecular Pain. 7: 14
Mantegazza M, Curia G, Biagini G, et al. (2010) Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders. The Lancet. Neurology. 9: 413-24
Ragsdale DS. (2008) How do mutant Nav1.1 sodium channels cause epilepsy? Brain Research Reviews. 58: 149-59
Wang X, Ponoran TA, Rasmusson RL, et al. (2005) Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents. Biophysical Journal. 89: 1731-43
Lucas PT, Meadows LS, Nicholls J, et al. (2005) An epilepsy mutation in the beta1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin. Epilepsy Research. 64: 77-84
Huang L, Keyser BM, Tagmose TM, et al. (2004) NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels. The Journal of Pharmacology and Experimental Therapeutics. 309: 193-9
Agrawal N, Alonso A, Ragsdale DS. (2003) Increased persistent sodium currents in rat entorhinal cortex layer V neurons in a post-status epilepticus model of temporal lobe epilepsy. Epilepsia. 44: 1601-4
Magistretti J, Ragsdale DS, Alonso A. (2003) Kinetic diversity of single-channel burst openings underlying persistent Na(+) current in entorhinal cortex neurons. Biophysical Journal. 85: 3019-34
De Leon L, Ragsdale DS. (2003) State-dependent access to the batrachotoxin receptor on the sodium channel. Neuroreport. 14: 1353-6
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