David S. Ragsdale

Affiliations: 
Neurology and Neurosurgery McGill University, Montreal, QC, Canada 
Area:
Sodium Channels, Calcium Channels, Epilepsy
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"David Ragsdale"
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Publications

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Behr C, Lévesque M, Ragsdale D, et al. (2015) Lacosamide modulates interictal spiking and high-frequency oscillations in a model of mesial temporal lobe epilepsy. Epilepsy Research. 115: 8-16
Biagini G, D'Antuono M, Inaba Y, et al. (2015) Activity-dependent changes in excitability of perirhinal cortex networks in vitro. PflüGers Archiv : European Journal of Physiology. 467: 805-16
Mo G, Grant R, O'Donnell D, et al. (2011) Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C. Molecular Pain. 7: 14
Mantegazza M, Curia G, Biagini G, et al. (2010) Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders. The Lancet. Neurology. 9: 413-24
Biagini G, Baldelli E, Longo D, et al. (2008) Proepileptic influence of a focal vascular lesion affecting entorhinal cortex-CA3 connections after status epilepticus. Journal of Neuropathology and Experimental Neurology. 67: 687-701
Ragsdale DS. (2008) How do mutant Nav1.1 sodium channels cause epilepsy? Brain Research Reviews. 58: 149-59
Merlo D, Mollinari C, Inaba Y, et al. (2007) Reduced GABAB receptor subunit expression and paired-pulse depression in a genetic model of absence seizures. Neurobiology of Disease. 25: 631-41
Wang X, Ponoran TA, Rasmusson RL, et al. (2005) Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents. Biophysical Journal. 89: 1731-43
Lucas PT, Meadows LS, Nicholls J, et al. (2005) An epilepsy mutation in the beta1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin. Epilepsy Research. 64: 77-84
Huang L, Keyser BM, Tagmose TM, et al. (2004) NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels. The Journal of Pharmacology and Experimental Therapeutics. 309: 193-9
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