Steven U. Walkley, DVM

Neurosciences Albert Einstein College of Medicine, New York, New York, United States 
Lysosomal Disorders
"Steven Walkley"
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Mark Zervas grad student 2001 Yeshiva University (Cell Biology Tree)
Marjorie C. Gondre-Lewis grad student 2003 Yeshiva University (Anatomy Tree)
Cristin Davidson grad student 2013 Yeshiva University
Matthew C. Micsenyi grad student 2013 Yeshiva University
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Davidson J, Molitor E, Moores S, et al. (2019) 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids
Ory DS, Ottinger EA, Farhat NY, et al. (2017) Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1-2 trial. Lancet (London, England)
Boudewyn LC, Sikora J, Kuchar L, et al. (2017) N-butyl-deoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV. Neurobiology of Disease
Sikora J, Dworski S, Jones EE, et al. (2017) Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities. The American Journal of Pathology. 187: 864-883
Yang DS, Stavrides P, Kumar A, et al. (2017) Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice. Human Molecular Genetics
Walkley SU, Davidson CD, Jacoby J, et al. (2016) Fostering collaborative research for rare genetic disease: the example of niemann-pick type C disease. Orphanet Journal of Rare Diseases. 11: 161
Davidson CD, Fishman YI, Puskás I, et al. (2016) Efficacy and ototoxicity of different cyclodextrins in Niemann-Pick C disease. Annals of Clinical and Translational Neurology. 3: 366-80
Sikora J, Leddy J, Gulinello M, et al. (2016) X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. Disease Models & Mechanisms. 9: 13-23
Praggastis M, Tortelli B, Zhang J, et al. (2015) A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106
Herbert AS, Davidson C, Kuehne AI, et al. (2015) Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo. Mbio. 6: e00565-15
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