James B. Lok
Affiliations: | Cell and Molecular Biology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Parasitology Biology, Molecular Biology, Cell BiologyGoogle:
"James Lok"Children
Sign in to add trainee| Michelle L. Castelletto | grad student | 2009 | Penn |
| Jonathan D. Stoltzfus | grad student | 2013 | Penn |
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Publications
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| Lok JB, Kliewer SA, Mangelsdorf DJ. (2022) The 'nuclear option' revisited: Confirmation of Ss-daf-12 function and therapeutic potential in Strongyloides stercoralis and other parasitic nematode infections. Molecular and Biochemical Parasitology. 250: 111490 |
| Wang Z, Cheong MC, Tsien J, et al. (2021) Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in . Elife. 10 |
| Cheong MC, Wang Z, Jaleta TG, et al. (2021) Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite . Proceedings of the National Academy of Sciences of the United States of America. 118 |
| McCrea AR, Edgerton EB, Oliver GT, et al. (2021) A novel assay to isolate and quantify third-stage Dirofilaria immitis and Brugia malayi larvae emerging from individual Aedes aegypti. Parasites & Vectors. 14: 30 |
| Edgerton EB, McCrea AR, Berry CT, et al. (2020) Activation of mosquito immunity blocks the development of transmission-stage filarial nematodes. Proceedings of the National Academy of Sciences of the United States of America |
| Jaleta TG, Lok JB. (2019) Advances in the Molecular and Cellular Biology of spp. Current Tropical Medicine Reports. 6: 161-178 |
| Doyle SR, Sankaranarayanan G, Allan F, et al. (2019) Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing. Frontiers in Genetics. 10: 826 |
| Charuchaibovorn S, Sanprasert V, Sutthanont N, et al. (2019) Cry5B is active against in vitro. The American Journal of Tropical Medicine and Hygiene |
| Lok JB. (2019) CRISPR/Cas9 Mutagenesis and Expression of Dominant Mutant Transgenes as Functional Genomic Approaches in Parasitic Nematodes. Frontiers in Genetics. 10: 656 |
| Adams S, Pathak P, Shao H, et al. (2019) Liposome-based transfection enhances RNAi and CRISPR-mediated mutagenesis in non-model nematode systems. Scientific Reports. 9: 483 |