Gina M. Leinninger, Ph.D.

Affiliations: 
2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Neuroscience Biology
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Parents

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Eva L. Feldman grad student 2005 University of Michigan
 (IGF-I protects neurons against glucose -induced mitochondrial damage and apoptosis.)
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Publications

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Brown JA, Woodworth HL, Leinninger GM. (2015) To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance. Frontiers in Systems Neuroscience. 9: 9
Patterson CM, Wong JM, Leinninger GM, et al. (2015) Ventral tegmental area neurotensin signaling links the lateral hypothalamus to locomotor activity and striatal dopamine efflux in male mice. Endocrinology. 156: 1692-700
Goforth PB, Leinninger GM, Patterson CM, et al. (2014) Leptin acts via lateral hypothalamic area neurotensin neurons to inhibit orexin neurons by multiple GABA-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11405-15
McClain JL, Grubišić V, Fried D, et al. (2014) Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice. Gastroenterology. 146: 497-507.e1
Opland D, Sutton A, Woodworth H, et al. (2013) Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity. Molecular Metabolism. 2: 423-34
Kempadoo KA, Tourino C, Cho SL, et al. (2013) Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7618-26
Leinninger GM, Opland DM, Jo YH, et al. (2011) Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metabolism. 14: 313-23
Grossberg AJ, Zhu X, Leinninger GM, et al. (2011) Inflammation-induced lethargy is mediated by suppression of orexin neuron activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11376-86
Scheller EL, Leinninger GM, Hankenson KD, et al. (2011) Ectopic expression of Col2.3 and Col3.6 promoters in the brain and association with leptin signaling. Cells, Tissues, Organs. 194: 268-73
Leinninger GM. (2011) Lateral thinking about leptin: a review of leptin action via the lateral hypothalamus. Physiology & Behavior. 104: 572-81
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