Michael Lenaeus, Ph.D.

Affiliations: 
2010 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Molecular Biology
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"Michael Lenaeus"
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Cross-listing: Microtree

Parents

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David Engman grad student 2010 Northwestern (Microtree)
 (The internal quaternary ammonium receptor in KcsA.)
William A. Catterall research scientist University of Washington
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Publications

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Tonggu L, Wisedchaisri G, Gamal El-Din TM, et al. (2024) Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. Nature Communications. 15: 2306
Gamal El-Din TM, Lenaeus MJ. (2022) Fenestropathy of Voltage-Gated Sodium Channels. Frontiers in Pharmacology. 13: 842645
Jiang D, Banh R, Gamal El-Din TM, et al. (2021) Open-state structure and pore gating mechanism of the cardiac sodium channel. Cell
Jiang D, Shi H, Tonggu L, et al. (2019) Structure of the Cardiac Sodium Channel. Cell
Catterall WA, Lenaeus MJ, El-Din TMG. (2019) Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels. Annual Review of Pharmacology and Toxicology
Tang L, Gamal El-Din TM, Lenaeus MJ, et al. (2019) Structural Basis for Diltiazem Block of a Voltage-gated Ca2+ Channel. Molecular Pharmacology
Gamal El-Din TM, Lenaeus MJ, Zheng N, et al. (2018) Fenestrations control resting-state block of a voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 115: 13111-13116
Gamal El-Din TM, Lenaeus MJ, Ramanadane K, et al. (2018) Molecular dissection of multiphase inactivation of the bacterial sodium channel NaAb. The Journal of General Physiology
Gamal El-Din TM, Lenaeus MJ, Catterall WA. (2017) Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective. Handbook of Experimental Pharmacology
Lenaeus MJ, Gamal El-Din TM, Ing C, et al. (2017) Structures of closed and open states of a voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America
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