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Megan E. Filbin, Ph.D.

Affiliations: 
2012 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology, Biochemistry
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"Megan Filbin"
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Jeffrey Scott Kieft grad student 2012 University of Colorado, Denver
 (Mechanisms by which the hepatitis C virus internal ribosome entry site regulates the switch from translation initiation to elongation.)

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Publications

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Filbin ME, Kieft JS. (2016) Linking Α to Ω: diverse and dynamic RNA-based mechanisms to regulate gene expression by 5'-to-3' communication. F1000research. 5
Filbin ME, Vollmar BS, Shi D, et al. (2013) HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nature Structural & Molecular Biology. 20: 150-8
Filbin ME, Kieft JS. (2011) HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove. Rna (New York, N.Y.). 17: 1258-73
Wallace A, Filbin ME, Veo B, et al. (2010) The nematode eukaryotic translation initiation factor 4E/G complex works with a trans-spliced leader stem-loop to enable efficient translation of trimethylguanosine-capped RNAs. Molecular and Cellular Biology. 30: 1958-70
Constantineau J, Greason E, West M, et al. (2010) A synonymous variant in scavenger receptor, class B, type I gene is associated with lower SR-BI protein expression and function. Atherosclerosis. 210: 177-82
Filbin ME, Kieft JS. (2009) Toward a structural understanding of IRES RNA function. Current Opinion in Structural Biology. 19: 267-76
Hammond JA, Rambo RP, Filbin ME, et al. (2009) Comparison and functional implications of the 3D architectures of viral tRNA-like structures. Rna (New York, N.Y.). 15: 294-307
Constantineau J, Greason E, West M, et al. (2008) THE SYNONYMOUS VARIANT (RS5888/A350) WITHIN THE SCAVENGER RECEPTOR, CLASS B, TYPE I GENE IS ASSOCIATED WITH LOWER SR-BI PROTEIN EXPRESSION Atherosclerosis Supplements. 9: 34
Kieft JS, Costantino DA, Filbin ME, et al. (2007) Structural methods for studying IRES function. Methods in Enzymology. 430: 333-71
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