Heather J. Montgomery, Ph.D.

Affiliations: 
2004 University of Waterloo, Waterloo, ON, Canada 
Area:
Biochemistry
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"Heather Montgomery"
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J Guy Guillemette grad student 2004 University of Waterloo
 (Differences in the activation of endothelial and neuronal nitric oxide synthase by oxidized calmodulin, and multiphoton activation of a photo-sensitive nitric oxide synthase inhibitor.)
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Publications

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Montgomery HJ, Dupont AL, Leivo HE, et al. (2010) Cloning, Expression, and Purification of a Nitric Oxide Synthase-Like Protein from Bacillus cereus. Biochemistry Research International. 2010: 489892
Perdicakis B, Montgomery HJ, Guillemette JG, et al. (2005) Analysis of slow-binding enzyme inhibitors at elevated enzyme concentrations. Analytical Biochemistry. 337: 211-23
Perdicakis B, Montgomery HJ, Abbott GL, et al. (2005) Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor. Bioorganic & Medicinal Chemistry. 13: 47-57
Perdicakis B, Montgomery HJ, Guillemette JG, et al. (2004) Validation and characterization of uninhibited enzyme kinetics performed in multiwell plates. Analytical Biochemistry. 332: 122-36
Newman E, Spratt DE, Mosher J, et al. (2004) Differential activation of nitric-oxide synthase isozymes by calmodulin-troponin C chimeras. The Journal of Biological Chemistry. 279: 33547-57
Gao YT, Smith SM, Weinberg JB, et al. (2004) Thermodynamics of oxidation-reduction reactions in mammalian nitric-oxide synthase isoforms. The Journal of Biological Chemistry. 279: 18759-66
Montgomery HJ, Bartlett R, Perdicakis B, et al. (2003) Activation of constitutive nitric oxide synthases by oxidized calmodulin mutants. Biochemistry. 42: 7759-68
Fishlock D, Perdicakis B, Montgomery HJ, et al. (2003) Synthesis and evaluation of trans 3,4-cyclopropyl L-arginine analogues as isoform selective inhibitors of nitric oxide synthase. Bioorganic & Medicinal Chemistry. 11: 869-73
Montgomery HJ, Perdicakis B, Fishlock D, et al. (2002) Photo-control of nitric oxide synthase activity using a caged isoform specific inhibitor. Bioorganic & Medicinal Chemistry. 10: 1919-27
Montgomery HJ, Romanov V, Guillemette JG. (2000) Removal of a putative inhibitory element reduces the calcium-dependent calmodulin activation of neuronal nitric-oxide synthase. The Journal of Biological Chemistry. 275: 5052-8
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