Annat F. Ikin

Affiliations: 
Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Alzheimer's Disease
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"Annat Ikin"
Mean distance: 115954
 
Cross-listing: Alzheimer's Tree

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Publications

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Ikin AF, Causevic M, Pedrini S, et al. (2007) Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Molecular Neurodegeneration. 2: 23
Gandy S, Zhang YW, Ikin A, et al. (2007) Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. Journal of Neurochemistry. 102: 619-26
Ikin AF, Sabo SL, Lanier LM, et al. (2007) A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching. Molecular and Cellular Neurosciences. 35: 57-63
Gandy S, Zhang YW, Ikin A, et al. (2007) Erratum: Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo (Journal of Neurochemistry (2007) 102, (619-626)) Journal of Neurochemistry. 103
Gandy S, Zhang Y, Ikin A, et al. (2006) S4-03-01: Evidence that aberrant post-TGN trafficking of Alzheimer's APP is sufficient to elevate brain A-beta 42 and may underlie mutant presenilin action Alzheimer's & Dementia. 2: S71-S71
Pastorino L, Ikin AF, Lamprianou S, et al. (2004) BACE (beta-secretase) modulates the processing of APLP2 in vivo. Molecular and Cellular Neurosciences. 25: 642-9
Sabo SL, Ikin AF, Buxbaum JD, et al. (2003) The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5407-15
Pastorino L, Ikin AF, Nairn AC, et al. (2002) The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta). Molecular and Cellular Neurosciences. 19: 175-85
Sabo SL, Ikin AF. (2002) Cytosolic protein-protein interactions that regulate the amyloid precursor protein Drug Development Research. 56: 228-241
Sabo SL, Ikin AF, Buxbaum JD, et al. (2001) The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. The Journal of Cell Biology. 153: 1403-14
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