Aaron R. Hieb, Ph.D.

Affiliations: 
2006 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Biochemistry, General Biophysics, Molecular Biology
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Parents

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James A. Goodrich grad student 2006 CU Boulder
 (Architecture and mechanism of the human RNA polymerase II general transcription machinery.)
Joerg Langowski post-doc 2006-2009 Deutsches Krebsforschungszentrum (DKFZ)
Karolin Luger post-doc 2009-2014 Colorado State
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Publications

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White AE, Hieb AR, Luger K. (2016) A quantitative investigation of linker histone interactions with nucleosomes and chromatin. Scientific Reports. 6: 19122
Muthurajan UM, Hepler MR, Hieb AR, et al. (2014) Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone. Proceedings of the National Academy of Sciences of the United States of America. 111: 12752-7
Hieb AR, Gansen A, Böhm V, et al. (2014) The conformational state of the nucleosome entry-exit site modulates TATA box-specific TBP binding Nucleic Acids Research. 42: 7561-7576
Gansen A, Hieb AR, Böhm V, et al. (2013) Closing the gap between single molecule and bulk FRET analysis of nucleosomes. Plos One. 8: e57018
Fierz B, Kilic S, Hieb AR, et al. (2012) Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis. Journal of the American Chemical Society. 134: 19548-51
Winkler DD, Luger K, Hieb AR. (2012) Quantifying chromatin-associated interactions: the HI-FI system. Methods in Enzymology. 512: 243-74
Hieb AR, D'Arcy S, Kramer MA, et al. (2012) Fluorescence strategies for high-throughput quantification of protein interactions. Nucleic Acids Research. 40: e33
Winkler DD, Muthurajan UM, Hieb AR, et al. (2011) Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events. The Journal of Biological Chemistry. 286: 41883-92
Winheim S, Hieb AR, Silbermann M, et al. (2011) Deconstructing the late phase of vimentin assembly by total internal reflection fluorescence microscopy (TIRFM) Plos One. 6
Böhm V, Hieb AR, Andrews AJ, et al. (2011) Nucleosome accessibility governed by the dimer/tetramer interface. Nucleic Acids Research. 39: 3093-102
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