Erin D. Hugger, Ph.D.

Affiliations: 
2002 University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry, Cell Biology
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Ronald T. Borchardt grad student 2002 University of Kansas
 (The effects of commonly used polyethoxylated excipients on P-glycoprotein activity in vitro.)
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Garver E, Hugger ED, Shearn SP, et al. (2008) Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2492-8
Xiang H, McSurdy-Freed J, Moorthy GS, et al. (2006) Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor Journal of Pharmaceutical Sciences. 95: 2657-2672
Hugger ED, Cole CJ, Raub TJ, et al. (2003) Automated analysis of polyethylene glycol-induced inhibition of P-glycoprotein activity in vitro. Journal of Pharmaceutical Sciences. 92: 21-6
Hugger ED, Novak BL, Burton PS, et al. (2002) A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro. Journal of Pharmaceutical Sciences. 91: 1991-2002
Hugger ED, Audus KL, Borchardt RT. (2002) Effects of poly(ethylene glycol) on efflux transporter activity in Caco-2 cell monolayers. Journal of Pharmaceutical Sciences. 91: 1980-90
Gao J, Hugger ED, Beck-Westermeyer MS, et al. (2001) Estimating intestinal mucosal permeation of compounds using Caco-2 cell monolayers. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 7.2
Wang W, Camenisch G, Sane DC, et al. (2000) A coumarin-based prodrug strategy to improve the oral absorption of RGD peptidomimetics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 245-51
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