Mindi R. Walker, Ph.D.

Affiliations: 
2002 East Carolina University, Greenville, NC, United States 
Area:
Immunology
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"Mindi Walker"

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Mark D. Mannie grad student 2002 East Carolina University
 (T cell expression of MHC class II glycoproteins: Presentation of the self -peptide rat myelin basic protein induces tolerance in the Lewis rat model of EAE.)
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Publications

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Cao T, Soto A, Zhou W, et al. (2009) Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD). Cellular Immunology. 258: 65-71
Long SA, Walker MR, Rieck M, et al. (2009) Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. European Journal of Immunology. 39: 612-20
Long SA, Walker M, Mueller I, et al. (2007) Low Dose Antigen Promotes Induction of Both Foreign and Self Reactive Human CD25+Foxp3+ Regulatory T Cells from CD4+CD25-Foxp3- Peripheral T Cells Clinical Immunology. 123: S132-S133
Walker MR, Carson BD, Nepom GT, et al. (2005) De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4103-8
Mannie MD, Dawkins JG, Walker MR, et al. (2004) MHC class II biosynthesis by activated rat CD4+ T cells: development of repression in vitro and modulation by APC-derived signals. Cellular Immunology. 230: 33-43
Walker MR, Kasprowicz DJ, Gersuk VH, et al. (2003) Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. The Journal of Clinical Investigation. 112: 1437-43
Walker MR, Mannie MD. (2002) Acquisition of functional MHC class II/peptide complexes by T cells during thymic development and CNS-directed pathogenesis. Cellular Immunology. 218: 13-25
Mannie MD, Walker MR. (2001) Feedback activation of T-cell antigen-presenting cells during interactions with T-cell responders. Journal of Leukocyte Biology. 70: 252-60
Walker MR, Mannie MD. (2001) T cell recognition of rat myelin basic protein as a TCR antagonist inhibits reciprocal activation of antigen-presenting cells and engenders resistance to experimental autoimmune encephalomyelitis. European Journal of Immunology. 31: 1894-9
Walker MR, White GA, Nardella JP, et al. (1999) An autologous self-antigen differentially regulates expression of I-A glycoproteins and B7 costimulatory molecules on CD4- CD8- T helper cells. Journal of Leukocyte Biology. 66: 120-6
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