Timothy S. Davison, Ph.D.

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Medical Biophysics, Molecular Biology
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"Timothy Davison"
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Parents

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Cheryl Arrowsmith grad student 2004 University of Toronto
 (The p53 oligomerization domain: Sequence -structure relationships and the design and characterization of altered oligomeric states.)
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Publications

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Davison TS, Nie X, Ma W, et al. (2001) Structure and functionality of a designed p53 dimer. Journal of Molecular Biology. 307: 605-17
Noolandi J, Davison TS, Volkel AR, et al. (2000) A meanfield approach to the thermodynamics of a protein-solvent system with application to the oligomerization of the tumor suppressor p53. Proceedings of the National Academy of Sciences of the United States of America. 97: 9955-60
Davison TS, Vagner C, Kaghad M, et al. (1999) p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53. The Journal of Biological Chemistry. 274: 18709-14
Davison TS, Yin P, Nie E, et al. (1998) Characterization of the oligomerization defects of two p53 mutants found in families with Li-Fraumeni and Li-Fraumeni-like syndrome. Oncogene. 17: 651-6
Vaziri H, West MD, Allsopp RC, et al. (1997) ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. The Embo Journal. 16: 6018-33
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