Jasvinder K. Atwal, Ph.D.
Affiliations: | 2002 | McGill University, Montreal, QC, Canada |
Area:
Neuroscience BiologyGoogle:
"Jasvinder Atwal"Mean distance: 17.27 (cluster 11)
Parents
Sign in to add mentor| Freda Diane Miller | grad student | 2002 | McGill | |
| (Signalling mechanisms underlying Trk function in neonatal sympathetic neurons.) | ||||
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Publications
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| Ferl GZ, Fuji RN, Atwal JK, et al. (2020) Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer's Disease. Current Alzheimer Research |
| Meilandt WJ, Maloney JA, Imperio J, et al. (2019) Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ. Alzheimer's Research & Therapy. 11: 97 |
| Ferl GZ, Fuji RN, Atwal J, et al. (2017) [P1-109]: MATHEMATICAL MODEL OF AMYLOID BETA (Aβ) DYNAMICS TO ASSESS TARGET ENGAGEMENT OF SOLUBLE Aβ OLIGOMERS BY CRENEZUMAB IN THE ALZHEIMER's DISEASE BRAIN Alzheimer's & Dementia. 13: P282-P282 |
| Ultsch M, Li B, Maurer T, et al. (2016) Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin. Scientific Reports. 6: 39374 |
| Lee SH, Le Pichon CE, Adolfsson O, et al. (2016) Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Reports |
| Lee S, Le Pichon C, Adolfsson O, et al. (2015) P2-054: Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology Alzheimer's & Dementia. 11: P503-P504 |
| Wetzel-Smith MK, Hunkapiller J, Bhangale TR, et al. (2014) A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7 |
| Maloney JA, Bainbridge T, Gustafson A, et al. (2014) Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein. The Journal of Biological Chemistry. 289: 30990-1000 |
| Yu YJ, Zhang Y, Kenrick M, et al. (2011) Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target. Science Translational Medicine. 3: 84ra44 |
| Atwal JK, Chen Y, Chiu C, et al. (2011) A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Science Translational Medicine. 3: 84ra43 |