Jasvinder K. Atwal, Ph.D.

Affiliations: 
2002 McGill University, Montreal, QC, Canada 
Area:
Neuroscience Biology
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"Jasvinder Atwal"
Mean distance: 17.27 (cluster 11)
 

Parents

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Freda Diane Miller grad student 2002 McGill
 (Signalling mechanisms underlying Trk function in neonatal sympathetic neurons.)
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Publications

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Ferl GZ, Fuji RN, Atwal JK, et al. (2020) Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer's Disease. Current Alzheimer Research
Meilandt WJ, Maloney JA, Imperio J, et al. (2019) Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ. Alzheimer's Research & Therapy. 11: 97
Ferl GZ, Fuji RN, Atwal J, et al. (2017) [P1-109]: MATHEMATICAL MODEL OF AMYLOID BETA (Aβ) DYNAMICS TO ASSESS TARGET ENGAGEMENT OF SOLUBLE Aβ OLIGOMERS BY CRENEZUMAB IN THE ALZHEIMER's DISEASE BRAIN Alzheimer's & Dementia. 13: P282-P282
Ultsch M, Li B, Maurer T, et al. (2016) Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin. Scientific Reports. 6: 39374
Lee SH, Le Pichon CE, Adolfsson O, et al. (2016) Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Reports
Gadkar K, Yadav DB, Zuchero JY, et al. (2016) Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
Lee S, Le Pichon C, Adolfsson O, et al. (2015) P2-054: Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology Alzheimer's & Dementia. 11: P503-P504
Wetzel-Smith MK, Hunkapiller J, Bhangale TR, et al. (2014) A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7
Yu YJ, Atwal JK, Zhang Y, et al. (2014) Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154
Maloney JA, Bainbridge T, Gustafson A, et al. (2014) Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein. The Journal of Biological Chemistry. 289: 30990-1000
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