Michael F. Mesleh, Ph.D.
Affiliations: | 2004 | University of California, San Diego, La Jolla, CA |
Area:
Biochemistry, General Biophysics, Physical Chemistry, Cell BiologyGoogle:
"Michael Mesleh"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Stanley Opella | grad student | 2004 | UCSD | |
| (Orientation and NMR for membrane protein structure determination.) | ||||
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Publications
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| Reidenbach AG, Mesleh MF, Casalena D, et al. (2020) Multimodal small-molecule screening for human prion protein binders. The Journal of Biological Chemistry |
| Ranaghan MJ, Durney MA, Mesleh MF, et al. (2017) The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity. Biochemistry |
| Mesleh MF, Cross JB, Zhang J, et al. (2016) Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorganic & Medicinal Chemistry Letters |
| Chen C, Dyck B, Fleck BA, et al. (2008) Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 1346-9 |
| Mesleh MF, Shirley WA, Heise CE, et al. (2007) NMR structural characterization of a minimal peptide antagonist bound to the extracellular domain of the corticotropin-releasing factor1 receptor. The Journal of Biological Chemistry. 282: 6338-46 |
| Betz SF, Lio FM, Gao Y, et al. (2006) Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling. Journal of Medicinal Chemistry. 49: 6170-6 |
| Tucci FC, Hu T, Mesleh MF, et al. (2005) Atropisomeric property of 1-(2,6-difluorobenzyl)-3-[(2R)-amino-2-phenethyl] -5-(2-fluoro-3-methoxyphenyl)-6-methyluracil Chirality. 17: 559-564 |
| De Angelis AA, Jones DH, Grant CV, et al. (2005) NMR experiments on aligned samples of membrane proteins. Methods in Enzymology. 394: 350-82 |
| Howell SC, Mesleh MF, Opella SJ. (2005) NMR structure determination of a membrane protein with two transmembrane helices in micelles: MerF of the bacterial mercury detoxification system. Biochemistry. 44: 5196-206 |
| Nevzorov AA, Mesleh MF, Opella SJ. (2004) Structure determination of aligned samples of membrane proteins by NMR spectroscopy Magnetic Resonance in Chemistry. 42: 162-171 |