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Louis (Lou) Siminovitch, Ph.D., D.Sc.

Affiliations: 
Samuel Lunenfeld Research Institute Mount Sinai Hospital (University of Toronto). 
Area:
researcher into the genetic basis of muscular dystrophy and cystic fibrosis, and helped establish Ontario programs exploring genetic roots of cancer
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"Louis (Lou) Siminovitch"
Mean distance: 14.65 (cluster 18)
 		SNBCP
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Parents

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Robert Lloyd McIntosh grad student 1944 McGill (E-Tree)
 (The Preparation of disulphur decafluoride)
Jacques Lucien Monod grad student 1948-1953 Institut Pasteur
 (Info deduced from http://www.science.ca/scientists/scientistprofile.php?pID=399)

Children

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Harvey Eisen grad student
James D. Friesen grad student 1963 University of Toronto (Cell Biology Tree)
Cliff Stanners grad student 1963 University of Toronto

Collaborators

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A. F. Graham collaborator Connaught Laboratories (Cell Biology Tree)
James Edgar Till collaborator University of Toronto
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Publications

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Hidaka K, An G, Ip P, et al. (1985) Amphotericin B enhances efficiency of DNA-mediated gene transfer in mammalian cells. Somatic Cell and Molecular Genetics. 11: 109-15
Tsui FW, Andrulis IL, Murialdo H, et al. (1985) Amplification of the gene for histidyl-tRNA synthetase in histidinol-resistant Chinese hamster ovary cells. Molecular and Cellular Biology. 5: 2381-8
Ray PN, Siminovitch L, Andrulis IL. (1984) Molecular cloning of a cDNA for Chinese hamster ovary asparagine synthetase. Gene. 30: 1-9
Arpaia E, Ray PN, Siminovitch L. (1983) Isolation of mutants of CHO cells resistant to 6 (p-hydroxyphenylazo)-uracil II. Mutants auxotrophic for deoxypyrimidines. Somatic Cell Genetics. 9: 287-97
Arpaia E, Ray PN, Siminovitch L. (1983) Isolation of mutants of CHO cells resistant to 6(p-hydroxyphenylazo)-uracil I. A novel BrdU cross-resistant phenotype. Somatic Cell Genetics. 9: 269-86
Andrulis IL, Duff C, Evans-Blackler S, et al. (1983) Chromosomal alterations associated with overproduction of asparagine synthetase in albizziin-resistant Chinese hamster ovary cells. Molecular and Cellular Biology. 3: 391-8
An G, Hidaka K, Siminovitch L. (1982) Expression of bacterial beta-galactosidase in animal cells. Molecular and Cellular Biology. 2: 1628-32
Tsui LC, Breitman ML, Siminovitch L, et al. (1982) Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells. Cell. 30: 499-508
Breitman ML, Tsui LC, Buchwald M, et al. (1982) Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells. Molecular and Cellular Biology. 2: 966-76
Debenham PG, Kartner N, Siminovitch L, et al. (1982) DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression. Molecular and Cellular Biology. 2: 881-9
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