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Louis (Lou) Siminovitch, Ph.D., D.Sc.

Affiliations: 
Samuel Lunenfeld Research Institute Mount Sinai Hospital (University of Toronto). 
Area:
researcher into the genetic basis of muscular dystrophy and cystic fibrosis, and helped establish Ontario programs exploring genetic roots of cancer
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"Louis (Lou) Siminovitch"
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Parents

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Robert Lloyd McIntosh grad student 1944 McGill (E-Tree)
 (The Preparation of disulphur decafluoride)
Jacques Lucien Monod grad student 1948-1953 Institut Pasteur
 (Info deduced from http://www.science.ca/scientists/scientistprofile.php?pID=399)

Children

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Harvey Eisen grad student
Cliff Stanners grad student 1963 University of Toronto

Collaborators

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James Edgar Till collaborator University of Toronto
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Publications

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Tsui LC, Breitman ML, Siminovitch L, et al. (1982) Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells. Cell. 30: 499-508
Breitman ML, Tsui LC, Buchwald M, et al. (1982) Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells. Molecular and Cellular Biology. 2: 966-76
Gupta RS, Siminovitch L. (1980) Diphtheria toxin resistance in Chinese hamster cells: genetic and biochemical characteristics of the mutants affected in protein synthesis. Somatic Cell Genetics. 6: 361-79
Gupta RS, Siminovitch L. (1980) Pactamycin resistance in CHO cells: morphological changes induced by the drug in the wild-type and mutant cells. Journal of Cellular Physiology. 102: 305-16
Gupta RS, Siminovitch L. (1980) Genetic markers for quantitative mutagenesis studies in Chinese hamster ovary cells: characteristics of some recently developed selective systems. Mutation Research. 69: 113-26
Lewis WH, Srinivasan PR, Stokoe N, et al. (1980) Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA. Somatic Cell Genetics. 6: 333-47
Gupta RS, Siminovitch L. (1980) DRB resistance in Chinese hamster and human cells: genetic and biochemical characteristics of the selection system. Somatic Cell Genetics. 6: 151-69
Srinivasan PR, Gupta RS, Siminovitch L. (1980) Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis. Somatic Cell Genetics. 6: 567-82
Weksberg R, Buchwald M, Sargent P, et al. (1979) Specific cellular defects in patients with Fanconi anemia. Journal of Cellular Physiology. 101: 311-23
Meuth M, Trudel M, Siminovitch L. (1979) Selection of Chinese hamster cells auxotrophic for thymidine by 1-β-D-arabinofuranosyl cytosine Somatic Cell Genetics. 5: 303-318
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