George G. Brownlee, Ph.D.

Affiliations: 
Pathology University of Oxford, Oxford, United Kingdom 
Area:
first cloned and patented the production and clinical use of recombinant human blood clotting factor IX
Website:
http://en.wikipedia.org/wiki/Sir_William_Dunn_School_of_Pathology
Google:
"George Brownlee"
Bio:

http://www.ox.ac.uk/admissions/postgraduate_courses/course_guide/pathology.html

Mean distance: 15.84 (cluster 18)
 
SNBCP

Parents

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Frederick Sanger grad student 1963-1966 Oxford (Chemistry Tree)
 (deduced from http://www.filmandsound.ac.uk/collections/records/0028-0000-2584-0000-0-0000-0000-0.html)

Children

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Nicholas Proudfoot grad student MRC-LMB (Chemistry Tree)
Greg Winter grad student 1976-1980 MRC-LMB
Stanley Fields grad student 1981 MRC-LMB (Microtree)
BETA: Related publications

Publications

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Brownlee GG. (2014) Fred Sanger double nobel laureate: A biography Fred Sanger Double Nobel Laureate: a Biography. 1-196
Gabriel G, Klingel K, Otte A, et al. (2011) Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus. Nature Communications. 2: 156
Leung BW, Chen H, Brownlee GG. (2010) Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity. Virology. 401: 96-106
Dreger M, Leung BW, Brownlee GG, et al. (2009) A quantitative strategy to detect changes in accessibility of protein regions to chemical modification on heterodimerization. Protein Science : a Publication of the Protein Society. 18: 1448-58
Kashiwagi T, Leung BW, Deng T, et al. (2009) The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding. Plos One. 4: e5473
Chase G, Deng T, Fodor E, et al. (2008) Hsp90 inhibitors reduce influenza virus replication in cell culture. Virology. 377: 431-9
Vreede FT, Gifford H, Brownlee GG. (2008) Role of initiating nucleoside triphosphate concentrations in the regulation of influenza virus replication and transcription. Journal of Virology. 82: 6902-10
Maier HJ, Kashiwagi T, Hara K, et al. (2008) Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding. Virology. 370: 194-204
Vreede FT, Gifford H, Brownlee GG. (2008) Role of initiating nucleoside triphosphate concentrations in the regulation of influenza virus replication and transcription (Journal of Virology (2008) 82, 14 (6902-6910)) Journal of Virology. 82: 9304
Vreede FT, Brownlee GG. (2007) Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro. Journal of Virology. 81: 2196-204
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