Gloria C. Preza, Ph.D.

Affiliations: 
2011 University of California, Los Angeles, Los Angeles, CA 
Area:
Pathology, Pharmacy, Pharmaceutical Chemistry
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"Gloria Preza"
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Tomas Ganz grad student 2011 UCLA
 (Hepcidin-Ferroportin Interactions: Targeting by Rational Drug Design.)
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Publications

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Clark RJ, Preza GC, Tan CC, et al. (2013) Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 100: 519-26
Preza GC, Pinon R, Ganz T, et al. (2013) Cellular catabolism of the iron-regulatory peptide hormone hepcidin. Plos One. 8: e58934
Ramos E, Ruchala P, Goodnough JB, et al. (2012) Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 120: 3829-36
Preza GC, Ruchala P, Pinon R, et al. (2011) Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. The Journal of Clinical Investigation. 121: 4880-8
Clark RJ, Tan CC, Preza GC, et al. (2011) Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry & Biology. 18: 336-43
Nemeth E, Ramos E, Ruchala P, et al. (2011) Mini-Hepcidins Prevent Iron Overload In A Mouse Model of Hereditary Hemochromatosis Blood. 118: 689-689
Fernandes A, Preza GC, Phung Y, et al. (2009) The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 114: 437-43
Preza G, Fernandes A, Clark RJ, et al. (2008) Structural Aspects of Hepcidin-Ferroportin Binding Blood. 112: 119-119
Nemeth E, Preza GC, Jung CL, et al. (2006) The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood. 107: 328-33
Porter E, Yang H, Yavagal S, et al. (2005) Distinct defensin profiles in Neisseria gonorrhoeae and Chlamydia trachomatis urethritis reveal novel epithelial cell-neutrophil interactions. Infection and Immunity. 73: 4823-33
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