Maciej J. Zamek-Gliszczynski, Ph.D.

Affiliations: 
2006 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology
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"Maciej Zamek-Gliszczynski"
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Kim L.R. Brouwer grad student 2006 UNC Chapel Hill
 (Mechanisms of hepatic transport of sulfate and glucuronide metabolites.)
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Publications

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Galetin A, Brouwer KLR, Tweedie D, et al. (2024) Membrane transporters in drug development and as determinants of precision medicine. Nature Reviews. Drug Discovery
Barth A, Perry CR, Shabbir S, et al. (2023) Clinical Assessment of Gepotidacin (GSK2140944) as a Victim and Perpetrator of Drug-Drug Interactions via CYP3A Metabolism and Transporters. Clinical and Translational Science
Taskar KS, Yang X, Neuhoff S, et al. (2022) Clinical relevance of hepatic and renal P-gp/BCRP inhibition of drugs: An International Transporter Consortium perspective. Clinical Pharmacology and Therapeutics
Zamek-Gliszczynski MJ, Sangha V, Shen H, et al. (2022) Transporters in drug development: International transporter consortium update on emerging transporters of clinical importance. Clinical Pharmacology and Therapeutics
Unger MS, Schumacher L, Enzlein T, et al. (2020) Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs. Analytical Chemistry. 92: 11851-11859
Zamek-Gliszczynski MJ, Patel M, Yang X, et al. (2020) Intestinal P-gp and Putative Hepatic OATP1B Induction: ITC Perspective on Drug Development Implications. Clinical Pharmacology and Therapeutics
Unger MS, Mudunuru J, Schwab M, et al. (2019) Clinically-relevant OATP2B1 inhibitors in marketed drug space. Molecular Pharmaceutics
Patel M, Eberl HC, Wolf A, et al. (2019) Mechanistic basis of cabotegravir-glucuronide disposition in humans. The Journal of Pharmacology and Experimental Therapeutics
Zamek-Gliszczynski MJ, Zhang X, Mudunuru J, et al. (2019) Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Zamek-Gliszczynski MJ, Taub ME, Chothe PP, et al. (2018) Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance. Clinical Pharmacology and Therapeutics
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