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Shala L. Thomas, Ph.D.

Affiliations: 
2009 Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Oncology, Pharmacology
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Haian Fu grad student 2009 Emory
 (Analysis of the EF24-modulated signaling pathways for the development of novel cancer combination therapies.)

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Thomas SL, Zhao J, Li Z, et al. (2010) Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy. Biochemical Pharmacology. 80: 1309-16
Thomas SL, Zhong D, Zhou W, et al. (2008) EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1. Cell Cycle (Georgetown, Tex.). 7: 2409-17
Kasinski AL, Du Y, Thomas SL, et al. (2008) Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Molecular Pharmacology. 74: 654-61
Marcus AI, O'Brate AM, Buey RM, et al. (2006) Farnesyltransferase inhibitors reverse taxane resistance. Cancer Research. 66: 8838-46
Marcus AI, Peters U, Thomas SL, et al. (2005) Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells. The Journal of Biological Chemistry. 280: 11569-77
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