Hovhannes J. Gukasyan, Ph.D.

Affiliations: 
2004 University of Southern California, Los Angeles, CA, United States 
Area:
Pharmacology, Ophthalmology, Pharmacy
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Vincent H. L. Lee grad student 2004 USC (Chemistry Tree)
 (Oxidation induced changes in conjunctival ion transport: Critical role of conjunctival GSH metabolism and transport in ocular surface health.)
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Publications

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Gukasyan HJ, Uchiyama T, Kim KJ, et al. (2017) Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2. Pharmaceutical Research
Zou HY, Engstrom LR, Li Q, et al. (2013) Abstract A277: PF-06463922, a novel ROS1/ALK inhibitor, demonstrates sub-nanomolar potency against oncogenic ROS1 fusions and capable of blocking the resistant ROS1G2032R mutant in preclinical tumor models. Molecular Cancer Therapeutics. 12
Prasanna G, Carreiro S, Anderson S, et al. (2011) Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma. Experimental Eye Research. 93: 256-64
Zou HY, Li Q, Lee J, et al. (2011) Abstract LB-390: Antitumor efficacy of crizotinib (PF-02341066), a potent and selective ALK and c-Met RTK inhibitor, in EML4-ALK driven NSCLC tumors in vitro and in vivo Cancer Research. 71
Prasanna G, Fortner J, Xiang C, et al. (2009) Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models. Experimental Eye Research. 89: 608-17
Carreiro S, Anderson S, Gukasyan HJ, et al. (2009) Correlation of in vitro and in vivo kinetics of nitric oxide donors in ocular tissues. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 25: 105-12
Uchiyama T, Fujita T, Gukasyan HJ, et al. (2008) Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes. Journal of Cellular Physiology. 214: 645-54
Gukasyan HJ, Kim KJ, Lee VH, et al. (2007) Glutathione and its transporters in ocular surface defense. The Ocular Surface. 5: 269-79
Selvam S, Thomas PB, Gukasyan HJ, et al. (2007) Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds. American Journal of Physiology. Cell Physiology. 293: C1412-9
Marra M, Gukasyan HJ, Raghava S, et al. (2007) 2nd Ophthalmic Drug Development and Delivery Summit. Expert Opinion On Drug Delivery. 4: 77-85
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