Rebecca J. Fairclough, D.Phil.

Affiliations: 
Physiology, Anatomy and Genetics University of Oxford, Oxford, United Kingdom 
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"Rebecca Fairclough"
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Publications

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Vuorinen A, Wilkinson IVL, Chatzopoulou M, et al. (2021) Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. European Journal of Medicinal Chemistry. 220: 113431
Araujo N, Vuorinen A, Fairclough R, et al. (2015) Discovery of small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 25: S260
Fairclough R, Squire S, Araujo N, et al. (2014) P13 New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 24: S10
Tinsley J, Bracchi A, Wilson F, et al. (2014) P10 Utrophin modulators to treat Duchenne Muscular Dystrophy (DMD): Future clinical trial plans for SMT C1100 and biomarker development programme Neuromuscular Disorders. 24: S9
Fairclough R, Guiraud S, Squire S, et al. (2014) G.P.89 Neuromuscular Disorders. 24: 821
Fairclough RJ, Wood MJ, Davies KE. (2013) Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches. Nature Reviews. Genetics. 14: 373-8
Tinsley J, Robinson N, Wilson F, et al. (2013) P.13.14 Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD) Neuromuscular Disorders. 23: 813
Fairclough RJ, Perkins KJ, Davies KE. (2012) Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy. Current Gene Therapy. 12: 206-44
Fairclough R, Squire S, Potter A, et al. (2012) O01 Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 22: S3
Fairclough RJ, Bareja A, Davies KE. (2011) Progress in therapy for Duchenne muscular dystrophy. Experimental Physiology. 96: 1101-13
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