Megumi Hirose, Ph.D.

Affiliations: 
Columbia University, New York, NY 
Area:
Brain development, stem cells
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"Megumi Hirose"
Mean distance: 16.81 (cluster 11)
 
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Publications

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Hirose M, Niewiadomski P, Tse G, et al. (2011) Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures. Journal of Neuroscience Research. 89: 1363-74
Hirose M, Hashimoto H, Iga J, et al. (2006) Inhibition of self-renewal and induction of neural differentiation by PACAP in neural progenitor cells. Annals of the New York Academy of Sciences. 1070: 342-7
Shintani N, Suetake S, Hashimoto H, et al. (2005) Neuroprotective action of endogenous PACAP in cultured rat cortical neurons. Regulatory Peptides. 126: 123-8
Hirose M, Hashimoto H, Shintani N, et al. (2005) Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells. Regulatory Peptides. 126: 109-13
Hashimoto H, Kunugi A, Arakawa N, et al. (2003) Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes. Biochemical and Biophysical Research Communications. 311: 337-43
Sakai Y, Hashimoto H, Shintani N, et al. (2002) Involvement of intracellular Ca2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells. Regulatory Peptides. 109: 149-53
Shintani N, Mori W, Hashimoto H, et al. (2002) Defects in reproductive functions in PACAP-deficient female mice. Regulatory Peptides. 109: 45-8
Hashimoto H, Shintani N, Tanaka K, et al. (2001) Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proceedings of the National Academy of Sciences of the United States of America. 98: 13355-60
Sakai Y, Hashimoto H, Shintani N, et al. (2001) Involvement of p38 MAP kinase pathway in the synergistic activation of PACAP mRNA expression by NGF and PACAP in PC12h cells. Biochemical and Biophysical Research Communications. 285: 656-61
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