Brian Yordy, Ph.D.

Affiliations: 
2013 Immunobiology Yale University, New Haven, CT 
Area:
Immunology
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"Brian Yordy"

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Akiko Iwasaki grad student 2013 Yale
 (Autophagy, Type I Interferon, and the Dynamic Herpes Simplex Virus Host Relationship.)
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Publications

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Khoury-Hanold W, Yordy B, Kong P, et al. (2016) Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality. Cell Host & Microbe. 19: 788-99
Rongvaux A, Jackson R, Harman CC, et al. (2014) Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell. 159: 1563-77
Nish SA, Schenten D, Wunderlich FT, et al. (2014) T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 3: e01949
Schenten D, Nish SA, Yu S, et al. (2014) Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 40: 78-90
Yordy B, Iwasaki A. (2013) Cell type-dependent requirement of autophagy in HSV-1 antiviral defense. Autophagy. 9: 236-8
Yordy B, Tal MC, Hayashi K, et al. (2013) Autophagy and selective deployment of Atg proteins in antiviral defense. International Immunology. 25: 1-10
Yordy B, Iijima N, Huttner A, et al. (2012) A neuron-specific role for autophagy in antiviral defense against herpes simplex virus. Cell Host & Microbe. 12: 334-45
Yordy B, Iwasaki A. (2011) Autophagy in the control and pathogenesis of viral infection. Current Opinion in Virology. 1: 196-203
Tal MC, Sasai M, Lee HK, et al. (2009) Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 2770-5
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