Leslie M. Tompkins, Ph.D.
Affiliations: | 2007 | North Carolina State University, Raleigh, NC |
Area:
Toxicology, Molecular BiologyGoogle:
"Leslie Tompkins"Mean distance: 14248.8
Parents
Sign in to add mentor| Robert C. Smart | grad student | 2007 | NCSU | |
| (Identification of novel transcription start sites and distinct proximal promoter regions for pregnane X receptor (PXR) isoforms PXR 1 and PXR 2.) | ||||
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Publications
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| Tompkins LM, Li H, Li L, et al. (2010) A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells. Biochemical Pharmacology. 80: 1754-61 |
| Tompkins L, Lynch C, Haidar S, et al. (2010) Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharmaceutical Research. 27: 1703-12 |
| Chen T, Tompkins LM, Li L, et al. (2010) A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3. The Journal of Pharmacology and Experimental Therapeutics. 332: 106-15 |
| Wang H, Tompkins LM. (2008) CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Current Drug Metabolism. 9: 598-610 |
| Tompkins LM, Sit TL, Wallace AD. (2008) Unique transcription start sites and distinct promoter regions differentiate the pregnane X receptor (PXR) isoforms PXR 1 and PXR 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 923-9 |
| Tompkins LM, Wallace AD. (2007) Mechanisms of cytochrome P450 induction. Journal of Biochemical and Molecular Toxicology. 21: 176-81 |