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Tina K. Machu

Affiliations: 
Biomedical Sciences University of North Texas Health Science Center at Fort Worth 
Area:
Molecular Biology, Neuroscience Biology, Physiology Biology
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"Tina Machu"
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Andreia N. de Oliveira-Pierce grad student 2009 University of North Texas Health Science Center at Fort Worth

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Publications

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Machu TK. (2011) Therapeutics of 5-HT3 receptor antagonists: current uses and future directions. Pharmacology & Therapeutics. 130: 338-47
de Oliveira-Pierce AN, Zhang R, Machu TK. (2009) Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptor. The Journal of Pharmacology and Experimental Therapeutics. 329: 838-47
Zhang R, Wen X, Militante J, et al. (2007) The role of loop F residues in determining differential d-tubocurarine potencies in mouse and human 5-hydroxytryptamine 3A receptors. Biochemistry. 46: 1194-204
Zhang R, White NA, Soti FS, et al. (2006) N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. The Journal of Pharmacology and Experimental Therapeutics. 317: 1276-84
Hu XQ, Hayrapetyan V, Gadhiya JJ, et al. (2006) Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions. British Journal of Pharmacology. 148: 88-101
Davies DL, Asatryan L, Kuo ST, et al. (2006) Effects of ethanol on adenosine 5'-triphosphate-gated purinergic and 5-hydroxytryptamine receptors. Alcoholism, Clinical and Experimental Research. 30: 349-58
Sessoms-Sikes JS, Hamilton ME, Liu LX, et al. (2003) A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions. The Journal of Pharmacology and Experimental Therapeutics. 306: 595-604
Das P, Bell-Horner CL, Machu TK, et al. (2003) The GABA(A) receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors. Neuropharmacology. 44: 431-8
Coultrap SJ, Machu TK. (2002) Enhancement of 5-hydroxytryptamine3A receptor function by phorbol 12-myristate, 13-acetate is mediated by protein kinase C and tyrosine kinase activity. Receptors & Channels. 8: 63-70
Davies DL, Machu TK, Guo Y, et al. (2002) Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent. Alcoholism, Clinical and Experimental Research. 26: 773-8
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