Marian Fundytus, PhD

Affiliations: 
Purdue Pharma 
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"Marian Fundytus"
Mean distance: 15.13 (cluster 37)
 
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Publications

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Whiteside GT, Harrison JE, Pearson MS, et al. (2004) DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted Mu opioid agonist with antihyperalgesic activity: II. In vivo pharmacological characterization in the rat. The Journal of Pharmacology and Experimental Therapeutics. 310: 793-9
Sharma SK, Yashpal K, Fundytus ME, et al. (2003) Alterations in brain metabolism induced by chronic morphine treatment: NMR studies in rat CNS. Neurochemical Research. 28: 1369-73
Fundytus ME, Osborne MG, Henry JL, et al. (2002) Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation. Pharmacology, Biochemistry, and Behavior. 73: 401-10
Sharif RN, Osborne M, Coderre TJ, et al. (2002) Attenuation of morphine tolerance after antisense oligonucleotide knock-down of spinal mGluR1. British Journal of Pharmacology. 136: 865-72
Fundytus ME. (2001) Glutamate receptors and nociception: implications for the drug treatment of pain. Cns Drugs. 15: 29-58
Fundytus ME, Yashpal K, Chabot JG, et al. (2001) Knockdown of spinal metabotropic glutamate receptor 1 (mGluR(1)) alleviates pain and restores opioid efficacy after nerve injury in rats. British Journal of Pharmacology. 132: 354-67
Fundytus ME. (2000) Common mechanisms underlying opioid tolerance and dependence, and neuropathic pain: Role of metabotropic glutamate receptors Pain Research and Management. 5: 40-48
Schiller PW, Fundytus ME, Merovitz L, et al. (1999) The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats. Journal of Medicinal Chemistry. 42: 3520-6
Fundytus ME, Coderre TJ. (1999) mGluRs and opioid dependence Pain Forum. 8: 59-63
Fundytus ME, Coderre TJ. (1999) Opioid tolerance and dependence Pain Forum. 8: 3-13
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