Shirly Pinto, PhD

Affiliations: 
Merck, Semoy, Centre-Val de Loire, France 
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"Shirly Pinto"
Mean distance: 16.4 (cluster 36)
 
SNBCP

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Tim Tully grad student 1994-2000 Weill Cornell Medical College
 (The latheo mutation disrupts neuronal proliferation and olfactory learning in Drosophila melanogaster.)
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Publications

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Imbriglio JE, Shen DM, Liang R, et al. (2015) The Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitors. Journal of Medicinal Chemistry
Song XS, Zhang J, Chen X, et al. (2015) Identification of DGAT2 Inhibitors Using Mass Spectrometry. Journal of Biomolecular Screening
Camus G, Schweiger M, Herker E, et al. (2014) The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets. The Journal of Biological Chemistry. 289: 35770-80
He S, Hong Q, Lai Z, et al. (2014) Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety. Acs Medicinal Chemistry Letters. 5: 1082-7
Graham TH, Shu M, Verras A, et al. (2014) Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 1657-60
Muise ES, Zhu Y, Verras A, et al. (2014) Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors. Plos One. 9: e88908
He S, Hong Q, Lai Z, et al. (2013) Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety. Acs Medicinal Chemistry Letters. 4: 773-8
Debenham JS, Graham TH, Verras A, et al. (2013) Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6228-33
DeVita RJ, Pinto S. (2013) Current status of the research and development of diacylglycerol O-acyltransferase 1 (DGAT1) inhibitors. Journal of Medicinal Chemistry. 56: 9820-5
Han S, Akiyama TE, Previs SF, et al. (2013) Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice. Journal of Lipid Research. 54: 2615-22
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