Huanchen Wang, Ph.D.
Affiliations: | 2006 | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Biochemistry, General Biophysics, Molecular BiologyGoogle:
"Huanchen Wang"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Hengming Ke | grad student | 2006 | UNC Chapel Hill | |
| (Structural studies on substrate and inhibitor selectivity of phosphodiesterases.) | ||||
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Publications
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| Gupta R, Liu Y, Wang H, et al. (2020) Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway. Journal of Molecular Biology |
| Li X, Gu C, Hostachy S, et al. (2020) Control of XPR1-dependent cellular phosphate efflux by InsP is an exemplar for functionally-exclusive inositol pyrophosphate signaling. Proceedings of the National Academy of Sciences of the United States of America |
| Randall TA, Gu C, Li X, et al. (2019) A two-way switch for inositol pyrophosphate signaling: Evolutionary history and biological significance of a unique, bifunctional kinase/phosphatase. Advances in Biological Regulation. 100674 |
| Riley AM, Wang H, Shears SB, et al. (2019) Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP. Medchemcomm. 10: 1165-1172 |
| An Y, Jessen HJ, Wang H, et al. (2019) Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine. Structure (London, England : 1993) |
| Gu C, Stashko MA, Puhl-Rubio A, et al. (2019) Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure/Activity Analysis. Journal of Medicinal Chemistry |
| Shears SB, Wang H. (2018) Inositol phosphate kinases: Expanding the biological significance of the universal core of the protein kinase fold. Advances in Biological Regulation |
| Yao T, Huang Y, Zhang M, et al. (2018) Crystal structures of Candida albicans phosphodiesterase-2 and implication on its biological functions. Biochemistry |
| Feng X, Wang H, Ye M, et al. (2018) Identification of a PDE4-specific pocket for design of selective inhibitors. Biochemistry |
| Wang H, Gu C, Rolfes RJ, et al. (2018) Structural and biochemical characterization of Siw14: a protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates. The Journal of Biological Chemistry |