Jonathan S. Marchant

Affiliations: 
Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmacology, Molecular Biology, Neuroscience Biology, Cell Biology
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"Jonathan Marchant"
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Children

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Kristen L. Woodhouse research assistant 2014-2018 UMN
Lisbeth C. Robinson grad student 2008 UMN
Yaping L. Moshier grad student 2012 UMN
Daniel J. Sprague post-doc 2021- Medical College of Wisconsin (Chemistry Tree)
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Publications

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Yuan Y, Arige V, Saito R, et al. (2023) Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca signals between lysosomes and the endoplasmic reticulum. Cell Reports. 43: 113628
Park SK, Sprague DJ, Rohr CM, et al. (2023) The anthelmintic meclonazepam activates a schistosome transient receptor potential channel. The Journal of Biological Chemistry. 300: 105528
Sprague DJ, Kaethner M, Park SK, et al. (2023) The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM Orthologs. Acs Medicinal Chemistry Letters. 14: 1537-1543
Gunaratne GS, Kumar S, Lin-Moshier Y, et al. (2023) Progesterone receptor membrane component 1 facilitates Ca signal amplification between endosomes and the endoplasmic reticulum. The Journal of Biological Chemistry. 105378
Sprague DJ, Park SK, Gramberg S, et al. (2023) Target-based discovery of a broad spectrum flukicide. Biorxiv : the Preprint Server For Biology
Saito R, Mu Q, Yuan Y, et al. (2023) Convergent activation of Ca permeability in two-pore channel 2 through distinct molecular routes. Science Signaling. 16: eadg0661
Gunaratne GS, Brailoiu E, Kumar S, et al. (2023) Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12. Science Signaling. 16: eadg0485
Yahya NA, Lanham JK, Sprague DJ, et al. (2023) Molecular and cellular basis of praziquantel action in the cardiovascular system. American Journal of Physiology. Cell Physiology
Chulkov EG, Palygin O, Yahya NA, et al. (2023) Electrophysiological characterization of a schistosome transient receptor potential channel activated by praziquantel. International Journal For Parasitology
Rohr CM, Sprague DJ, Park SK, et al. (2022) Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217732120
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