Rene Maltais, Ph.D.
Affiliations: | 2001 | Universite Laval (Canada) |
Area:
Pharmaceutical ChemistryGoogle:
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Parents
Sign in to add mentor| Donald Poirier | grad student | 2001 | Universite Laval (Canada) | |
| (Mise au point de nouvelles methodes de synthese combinatoire de derives steroidiens de type sulfamate, cetone et hydroxyle pour bloquer les effets proliferatifs des androgenes.) | ||||
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Publications
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| Fortin N, Hénaut M, Goyette N, et al. (2024) A protectin DX (PDX) analog with in vitro activity against influenza A(H1N1) viruses. Journal of Medical Virology. 96: e29484 |
| Burguin A, Roy J, Ouellette G, et al. (2023) Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments. Journal of Clinical Medicine. 12 |
| Poirier D, Roy J, Maltais R, et al. (2023) An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models. Cancers. 15 |
| Maltais R, Sancéau JY, Poirier D, et al. (2023) A Concise, Gram-Scale Total Synthesis of Protectin DX and Related Labeled Versions via a Key Stereoselective Reduction of Enediyne. The Journal of Organic Chemistry |
| Ngueta AD, Roy J, Maltais R, et al. (2023) Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone. Molecules (Basel, Switzerland). 28 |
| Poirier D, Maltais R, Rousseau JA, et al. (2022) Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution. Bioorganic Chemistry. 129: 106145 |
| Poirier D, Nyachieo A, Romano A, et al. (2022) An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis model. The Journal of Steroid Biochemistry and Molecular Biology. 106136 |
| Sancéau JY, Bélanger P, Maltais R, et al. (2022) An Improved Synthesis of Glucuronide Metabolites of Hindered Phenolic Xenoestrogens. Current Organic Synthesis |
| Maltais R, Roy J, Perreault M, et al. (2021) Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel. International Journal of Molecular Sciences. 22 |
| Maltais R, Roy J, Poirier D. (2021) Turning a Quinoline-based Steroidal Anticancer Agent into Fluorescent Dye for its Tracking by Cell Imaging. Acs Medicinal Chemistry Letters. 12: 822-826 |