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Adele M. Stewart, Ph.D.

Affiliations: 
2014 Pharmacology University of Iowa, Iowa City, IA 
Area:
Pharmacology, Neuroscience Biology
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"Adele Stewart"
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Rory A. Fisher grad student 2014 University of Iowa
 (Regulator of G protein signaling 6 (RGS6), a multifarious and pleiotropic modulator of G protein coupled receptor signaling in brain.)

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Publications

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Basak M, Sengar AS, Das K, et al. (2022) A RGS7-CaMKII complex drives myocyte-intrinsic and myocyte-extrinsic mechanisms of chemotherapy-induced cardiotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2213537120
Das K, Basak M, Mahata T, et al. (2022) RGS11-CaMKII complex mediated redox control attenuates chemotherapy-induced cardiac fibrosis. Redox Biology. 57: 102487
Maity B, Chakraborti S, Pramanick A, et al. (2017) Atypical G protein β5 promotes cardiac oxidative stress, apoptosis, and fibrotic remodeling in response to multiple cancer chemotherapeutics. Cancer Research
Stewart A, Maity B, Fisher RA. (2015) Two for the Price of One: G Protein-Dependent and -Independent Functions of RGS6 In Vivo. Progress in Molecular Biology and Translational Science. 133: 123-51
Stewart A, Fisher RA. (2015) Introduction: G Protein-coupled Receptors and RGS Proteins. Progress in Molecular Biology and Translational Science. 133: 1-11
Stewart A, Maity B, Anderegg SP, et al. (2015) Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol. Proceedings of the National Academy of Sciences of the United States of America. 112: E786-95
Stewart A, Maity B, Wunsch AM, et al. (2014) Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1735-44
Huang J, Stewart A, Maity B, et al. (2014) RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis. Oncogene. 33: 3604-11
Maity B, Stewart A, O'Malley Y, et al. (2013) Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression. Carcinogenesis. 34: 1747-55
Yang J, Maity B, Huang J, et al. (2013) G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin. Cancer Research. 73: 1662-7
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