Nga Bien-Ly, Ph.D.
Affiliations: | Neuroscience | Genentech, Inc., San Francisco, CA, United States |
Area:
Blood-brian barrierGoogle:
"Nga Bien-Ly"Mean distance: 16.79 (cluster 11) | S | N | B | C | P |
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Publications
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| Xiong M, Jiang H, Serrano JR, et al. (2021) APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function. Science Translational Medicine. 13 |
| Liao F, Li A, Xiong M, et al. (2018) Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. The Journal of Clinical Investigation |
| Rajapaksa KS, Huang T, Sharma N, et al. (2016) Preclinical safety profile of a depleting antibody against CRTh2 for asthma: Well tolerated despite unexpected CRTh2 expression on vascular pericytes in the central nervous system and gastric mucosa. Toxicological Sciences : An Official Journal of the Society of Toxicology |
| Zuchero YJ, Chen X, Bien-Ly N, et al. (2015) Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron |
| Bien-Ly N, Boswell CA, Jeet S, et al. (2015) Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron. 88: 289-97 |
| Huntley MA, Bien-Ly N, Daneman R, et al. (2014) Dissecting gene expression at the blood-brain barrier. Frontiers in Neuroscience. 8: 355 |
| Bien-Ly N, Watts RJ. (2014) The blood-brain barrier's gut check. Science Translational Medicine. 6: 263fs46 |
| Yu YJ, Atwal JK, Zhang Y, et al. (2014) Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154 |
| Bien-Ly N, Yu YJ, Bumbaca D, et al. (2014) Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. The Journal of Experimental Medicine. 211: 233-44 |
| Bien-Ly N, Gillespie AK, Walker D, et al. (2012) Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4803-11 |