Ian D. Coombs
Affiliations: | University College London, London, United Kingdom |
Area:
Ionotropic glutamate receptorsGoogle:
"Ian Coombs"Mean distance: 14.66 (cluster 11) | S | N | B | C | P |
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Publications
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| Coombs ID, Farrant M. (2023) An unexpected role for a glutamate receptor. Science (New York, N.Y.). 382: 1363-1364 |
| Coombs I, Bats C, Sexton CA, et al. (2023) Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM. Elife. 12 |
| Coombs ID, Ziobro J, Krotov V, et al. (2022) A gain-of-function GRIA2 variant associated with neurodevelopmental delay and seizures: functional characterization and targeted treatment. Epilepsia |
| Coombs ID, Sexton CA, Cull-Candy SG, et al. (2022) Influence of the TARP γ8-Selective Negative Allosteric Modulator JNJ-55511118 on AMPA Receptor Gating and Channel Conductance. Molecular Pharmacology. 101: 343-356 |
| Coombs ID, Cull-Candy SG. (2021) Single-channel mechanisms underlying the function, diversity and plasticity of AMPA receptors. Neuropharmacology. 108781 |
| Coombs ID, Soto D, McGee TP, et al. (2019) Homomeric GluA2(R) AMPA receptors can conduct when desensitized. Nature Communications. 10: 4312 |
| Coombs ID, MacLean DM, Jayaraman V, et al. (2017) Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation. Cell Reports. 20: 1123-1135 |
| Coombs I, Tarasiuk A, Marconi L, et al. (2017) Multiple Subconductance States of Tarped AMPA Receptors Revealed by Slow Dissociation of Antagonist Biophysical Journal. 112: 418a |
| Coombs ID, Soto D. (2016) Using electrophysiology to study synaptic and extrasynaptic ionotropic receptors in hippocampal neurons Neuromethods. 110: 313-355 |
| Soto D, Coombs ID, Gratacòs-Batlle E, et al. (2014) Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11673-83 |