Fraydon Rastinejad

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
General Biophysics, Biochemistry, Cell Biology
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"Fraydon Rastinejad"
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Publications

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Li W, Hang S, Fang Y, et al. (2021) A bacterial bile acid metabolite modulates T activity through the nuclear hormone receptor NR4A1. Cell Host & Microbe
Smith S, McHale K, Creech K, et al. (2020) 595 Differential ligand binding distinguishes therapeutic from pathologic Aryl Hydrocarbon Receptor (AhR) modulating agents: Implications for inflammatory skin disease Journal of Investigative Dermatology. 140: S81
Daniel B, Nagy G, Czimmerer Z, et al. (2018) The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory. Immunity. 49: 615-626.e6
Chandra V, Wu D, Li S, et al. (2017) The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission. Nature Communications. 8: 868
Wu D, Su X, Potluri N, et al. (2016) NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife. 5
Khorasanizadeh S, Rastinejad F. (2016) Visualizing the Architectures and Interactions of Nuclear Receptors. Endocrinology. en20161559
Santori FR, Huang P, van de Pavert SA, et al. (2015) Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97
Rastinejad F, Ollendorff V, Polikarpov I. (2015) Nuclear receptor full-length architectures: confronting myth and illusion with high resolution. Trends in Biochemical Sciences. 40: 16-24
Huang P, Chandra V, Rastinejad F. (2014) Retinoic acid actions through mammalian nuclear receptors. Chemical Reviews. 114: 233-54
Rastinejad F, Huang P, Chandra V, et al. (2013) Understanding nuclear receptor form and function using structural biology. Journal of Molecular Endocrinology. 51: T1-T21
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