Olivia A. Perng, Ph.D.

Affiliations: 
2013 Immunology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Olivia Perng"

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Andrew J. Caton grad student 2013 Penn
 (The influence of CD4+ T cell affinity for self-antigen on the development of inflammatory arthritis.)
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Publications

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Perng OA, Aitken M, Rankin AL, et al. (2014) The degree of CD4+ T cell autoreactivity determines cellular pathways underlying inflammatory arthritis. Journal of Immunology (Baltimore, Md. : 1950). 192: 3043-56
Cozzo Picca C, Simons DM, Oh S, et al. (2011) CD4⁺CD25⁺Foxp3⁺ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletion. Proceedings of the National Academy of Sciences of the United States of America. 108: 14890-5
Simons DM, Picca CC, Oh S, et al. (2010) How specificity for self-peptides shapes the development and function of regulatory T cells. Journal of Leukocyte Biology. 88: 1099-107
Hondowicz BD, Batheja AO, Metzgar MH, et al. (2009) Efficient help for autoreactive B-cell activation requires CD4+ T-cell recognition of an agonist peptide at the effector stage. European Journal of Immunology. 39: 2377-82
Esashi E, Wang YH, Perng O, et al. (2008) The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity. 28: 509-20
Wei J, Duramad O, Perng OA, et al. (2007) Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 18169-74
Ito T, Yang M, Wang YH, et al. (2007) Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. The Journal of Experimental Medicine. 204: 105-15
Ito T, Wang YH, Duramad O, et al. (2006) OX40 ligand shuts down IL-10-producing regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 13138-43
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