Wen Xue, Ph.D.

Affiliations: 
2009 Stony Brook University, Stony Brook, NY, United States 
Area:
Cell Biology, Molecular Biology, Genetics
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"Wen Xue"

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Scott Lowe grad student 2009 SUNY Stony Brook
 (Probing tumor suppressor gene networks in hepatocarcinomas.)
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Publications

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Rodríguez TC, Kwan S, Smith JL, et al. (2022) Multi-omics characterization of mouse hepatoblastoma identifies novel YAP1 target genes. Hepatology (Baltimore, Md.)
Jiang T, Sánchez-Rivera FJ, Soto-Feliciano YM, et al. (2020) Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function. Hepatology (Baltimore, Md.)
Smith JL, Rodríguez TC, Mou H, et al. (2020) YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte-like cells. Hepatology (Baltimore, Md.)
Jiang T, Henderson JM, Coote K, et al. (2020) Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Nature Communications. 11: 1979
Wu SS, Li QC, Yin CQ, et al. (2020) Advances in CRISPR/Cas-based Gene Therapy in Human Genetic Diseases. Theranostics. 10: 4374-4382
Song CQ, Jiang T, Richter M, et al. (2019) Adenine base editing in an adult mouse model of tyrosinaemia. Nature Biomedical Engineering
Lee J, Mou H, Ibraheim R, et al. (2019) Tissue-restricted Genome Editing Specified by MicroRNA-repressible Anti-CRISPR Proteins. Rna (New York, N.Y.)
Kwan SY, Sheel A, Song CQ, et al. (2019) Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes. Hepatology (Baltimore, Md.)
Mou H, Ozata DM, Smith JL, et al. (2019) CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. Genome Medicine. 11: 21
Wang W, Yang J, Edin ML, et al. (2019) Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis. Cancer Research
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